Diacetylcurcumin: Its Potential Antiarthritic Effect on a Freund’s Complete Adjuvant-Induced Murine Model
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چکیده
منابع مشابه
Anti-arthritic Effect of 1'-acetoxychavicol Acetate in Complete Freunds Adjuvant-induced Arthritis in Rats
1'-Acetoxychavicol acetate (ACA) is a phenylpropanoid present in Alpinia galanga (L) Willd syn. Languas galanga. The objective of this study was to isolate 1'-Acetoxychavicol acetate (ACA) from acetone extract of Alpinia galanga (AEAG) and evaluate anti-arthritic activity of 1'-Acetoxychavicol acetate (ACA) and acetone extract of Alpinia galanga (AEAG) on complete Freund’s Adjuvant-induced arth...
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OBJECTIVES To formulate a polyherbal formulation and evaluate its antiarthritic activity against Freund's complete adjuvant induced arthritis in Female Wistar rats. MATERIALS AND METHODS Glycosmis pentaphylla, Tridax procumbens, and Mangifera indica are well-known plants available throughout India and they are commonly used for the treatment of various diseases including arthritis. The polyhe...
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Objective: The objective of the present study was to isolate galangin from methanolic extract of Alpinia officinarum (MEAO) by bioassay guided fractionation using hexane–ethyl acetate as a solvent and evaluated the anti-arthritic effect of galangin and MEAO in complete Freund’s adjuvant (CFA) induced arthritis in wistar rats. Methods: Arthritis was induced by intradermal injection of CFA into t...
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Objective The aim was to study the therapeutic effects and mechanisms of QWRG on adjuvant-induced RA in rats. Methods The RA rat models were manipulated and subsequently divided into five experimental groups: AIA, DEX, and QWRG groups. The paw volume, body weight, arthritic score, and mechanical nociceptive threshold were assessed. The serum levels of the RF, MDA, ALP, AST, ALT, IL-1β, IL-2, ...
متن کاملPotent Antiarthritic Properties of Phloretin in Murine Collagen-Induced Arthritis
In the exploration of potential therapeutic agents for rheumatoid arthritis (RA), DBA/1J mice are used as the RA model of collagen-induced arthritis (CIA). Phloretin, a flavonoid compound extracted from Prunus mandshurica, has been found to exhibit anti-inflammatory activity, making it a potential candidate for treatment of RA. The objective of this study was to evaluate the therapeutic effects...
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ژورنال
عنوان ژورنال: Molecules
سال: 2019
ISSN: 1420-3049
DOI: 10.3390/molecules24142643